2-Iodomelatonin 是褪黑激素受体 1 (MT1) 的有效激动剂,Ki 值为 28 pM,它对 MT1 的选择性比 MT2 高 5 倍。 2-碘褪黑激素可用于识别、表征和定位大脑和外周组织中的褪黑激素结合位点。
Cas No. | 93515-00-5 |
别名 | 2-碘褪黑激素 |
化学名 | N-(2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl)acetamide |
Canonical SMILES | IC1=C(CCNC(C)=O)C2=CC(OC)=CC=C2N1 |
分子式 | C13H15IN2O2 |
分子量 | 358.18 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 20 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |