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Oleamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oleamide图片
CAS NO:301-02-0
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
油酰胺是一种内源性脂肪酸酰胺,可在哺乳动物神经系统中从头合成,并已在人血浆中检测到。
Cas No.301-02-0
别名油酸酰胺
化学名oleamide
Canonical SMILESO=C(CCCCCCC/C=C\CCCCCCCC)N
分子式C18H35NO
分子量281.48
溶解度DMF: >14 mg/ml (from 13-Docosenamid,DMSO: >20 mg/ml (from 13-Docosenamid,Ethanol: >22 mg/ml (from 13-Docosenamid,PBS pH 7.2:<50 µ g/ml (from 13-Docosenamid
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.

Oleamide accumulates in the cerebrospinal fluid (CSF) of rats after six hours of sleep deprivation and induces sleep in naive rats and mice. Inhibition of the primary catabolic enzyme of oleamide (fatty acid amide hydrolase) by trifluoromethyl-octadecenone reduces sleep latency and increases total sleep time when given centrally to rats and peripherally to mice[1]

References:
[1]. Mendelson WB, et al. The hypnotic actions of the fatty acid amide, oleamide. Neuropsychopharmacology. 2001 Nov;25(5 Suppl):S36-9.