CAS NO: | 156856-31-4 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 156856-31-4 |
化学名 | 3-(4-deoxy-β-xylo-hexopyranosyl)-2-hydroxy-6-[(3E,5E,8Z)-2-hydroxy-7-(hydroxymethyl)-1,1,5,9,11-pentamethyl-3,5,8-heptadecatrien-1-yl]-2H-pyran-2-one |
Canonical SMILES | O[C@H]1C[C@@H](CO)O[C@@H](C2=C(O)OC(C(C)(C)C(O)/C=C/C(C)=C/C(CO)/C=C(C)\CC(C)CCCCCC)=CC2=O)[C@@H]1O |
分子式 | C34H54O9 |
分子量 | 606.8 |
溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Fusapyrone, a broad-spectrum antifungal metabolite, is isolated from several Fusarium species. Structurally, fusapyrone consists of a 4-deoxy-β-xylo-hexopyranosyl C-glycosyl moiety bound to the C-6 of the 2-pyrone ring and a highly functionalized aliphatic chain. Fusapyrone exhibited low zoo-toxicity, as evidenced by a lack of toxicity against Artemia salina. Fusapyrone exerted considerable antifungal activity against several plant mycotoxigenic, pathogenic, and human pathogenic filamentous fungi, including Aspergillus flavus, Aspergillus niger, Aspergillus parasiticus, and Aspergillus fumigatus [1]. Additionally, it had been investigated as a useful candidate for the control of postharvest crop diseases, including blocking the growth of ochratoxin-producing strains of Aspergillus section Nigri in wine grapes. However, fusapyrone was found to be ineffective toward yeasts isolated from fruits and plants and not toxic to Artemia salina (brine shrimp). The mechanism of action of fusapyrone is unknown and the structure of fusapyrone was revised in 2006. In vitro: Up to now, in vitro study of fusapyrone is still in the development stage. In vivo: Up to now, in vivo study of fusapyrone is still in the development stage. Reference: |