CAS NO: | 33564-30-6 |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
1g | 电议 |
Cas No. | 33564-30-6 |
别名 | 头孢西丁钠; MK-306 |
化学名 | (6R,7S)-3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt |
Canonical SMILES | O=C1[C@](NC(CC2=CC=CS2)=O)(OC)[C@]3([H])N1C(C([O-])=O)=C(COC(N)=O)CS3.[Na+] |
分子式 | C16H16N3O7S2o Na |
分子量 | 449.4 |
溶解度 | ≥ 12.9mg/mL in DMSO |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Cefoxitin (sodium salt) is a second generation cephalosporin antibiotic that was used to treat a wide range of gram-negative and gram-positive bacteria [1][2]. Cefoxitin, 3-carbamoyloxymethyl-7-a-methoxy-7- [2-(2-thienyl)acetamido]-3-cephem-4-carboxylic acid, is a semisynthetic cephamycin antibiotic with broad-spectrum activity. Cefoxitin is also active in vivo against a wide variety of bacteria including penicillin-resistant staphylococci and effective against gram-negative organisms including strains of indole-positive Proteus [1]. In mice, cefoxitin was more active against the cephalosporin-sensitive gram-negative bacteria, strains of E.coli, indole-producing Proteus, and Serratia, and the lactamase producing 2646. Cefoxitin was degraded by the lactamase of E. cloacae at a much slower rate than are the cephalosporins. In pharmacological studies, cefoxitin was found in sera and detected in urine samples in amounts greater than those of cephalothin and less than those of cephaloridine [1]. References: |