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Chrysomycin B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Chrysomycin B图片
CAS NO:83852-56-6
包装与价格:
包装价格(元)
250μg电议
1mg电议

产品介绍
Chrysomycin B 是一种从链霉菌菌株中分离出来的抗生素。 Chrysomycin B 在人肺腺癌 A549 细胞系中引起 DNA 损伤并抑制拓扑异构酶 II。 Chrysomycin B 抑制小鼠可移植肿瘤的生长。
Cas No.83852-56-6
别名金黄霉素B
化学名4-(6-deoxy-3-C-methyl-β-gulopyranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one
Canonical SMILESO=C(O1)C2=C(C(OC)=CC(C)=C2)C3=C1C4=C(C5OC(C)C(O)C(C)(O)C5O)C=CC(O)=C4C(OC)=C3
分子式C27H28O9
分子量496.5
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述 Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. It differs from its analog chrysomycin A by having a methyl, rather than vinyl, group in the 8-position of the chromophore. Like its analog, chrysomycin B suppresses the growth of transplantable tumors in mice, an effect that may be related to its ability to bind DNA. It also causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B is structurally very similar to gilvocarcin V, which promotes DNA cross-linking with histone 3 and GRP78 when photoactivated by near-UV light.