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Trofosfamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Trofosfamide图片
CAS NO:22089-22-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Trofosfamide 是一种具有抗肿瘤活性的口服生物可利用的恶氮磷衍生物。
Cas No.22089-22-1
别名曲磷胺
化学名N,N,3-tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine,2-oxide
Canonical SMILESClCCN(CCCl)P1(OCCCN1CCCl)=O
分子式C9H18Cl3N2O2P
分子量323.6
溶解度DMF: 50mg/mL,DMSO: 30mg/mL,Ethanol: 50mg/mL,PBS (pH 7.2): 10mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity[1].

References:
[1]. Witte HM, et al. Trofosfamide in the treatment of elderly or frail patients with diffuse large B-cell lymphoma. J Cancer Res Clin Oncol. 2019 Jan;145(1):129-136.
[2]. Gorn M, et al. A pilot study of docetaxel and trofosfamide as second-line 'metronomic' chemotherapy in the treatment of metastatic non-small cell lung cancer (NSCLC). Onkologie. 2008 Apr;31(4):185-9.