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Methylmalonate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Methylmalonate图片
CAS NO:516-05-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
500mg电议
1g电议

产品介绍
丙二酸甲酯 (Methylmalonate) 是癌症中维生素 B-12 缺乏的指标。
Cas No.516-05-2
别名甲基丙二酸; Methylpropanedioic acid; Methylmalonate
化学名2-methylmalonic acid
Canonical SMILESOC(C(C(O)=O)C)=O
分子式C4H6O4
分子量118.09
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.

Vitamin B-12 is required for Methylmalonate (Methylmalonic acid; MMA) to be converted to succinyl-CoA, and in combination with folic acid, for homocysteine (HC) to be converted to methionine. Therefore, Methylmalonate is clearly more specific to vitamin B-12 deficiency compared to HC[1].

References:
[1]. Vashi P, et al. Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. PLoS One. 2016 Jan 25;11(1):e0147843.