1-Deazaadenosine 是一种有效的腺苷脱氨酶 (ADA) 抑制剂,Ki 值为 0.66 μM。 1-Deazaadenosine 在体外表现出抗癌活性,并有可能成为淋巴组织增生性疾病的化疗药物。
Cas No. | 14432-09-8 |
别名 | 1-去氮杂腺苷 |
化学名 | (2S,3R,4S,5R)-2-(7-amino-3H-imidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
Canonical SMILES | O[C@H]1[C@@H](N2C3=NC=CC(N)=C3N=C2)O[C@H](CO)[C@H]1O |
分子式 | C11H14N4O4 |
分子量 | 266.25 |
溶解度 | <6.66mg/ml in DMSO |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |