RS 25344 hydrochloride 是一种选择性 cAMP-磷酸二酯酶 4 (PDE 4; PDE IV) 抑制剂，对人淋巴细胞的 IC50 为 0.28 nM。
| Cas No. | 152815-28-6 |
| 别名 | 1-(3-硝基苯基)-3-(吡啶-4-基甲基)吡啶并[2,3-D]嘧啶-2,4(1H,3H)-二酮盐酸盐 |
| 化学名 | 1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride |
| Canonical SMILES | O=C(N(C1=O)CC2=CC=NC=C2)C3=C(N1C4=CC(N(=O)=O)=CC=C4)N=CC=C3.Cl |
| 分子式 | C19H13N5O4.HCl |
| 分子量 | 411.8 |
| 溶解度 | <20.59mg/ml in Water;<41.18mg/ml in DMSO |
| 储存条件 | Desiccate at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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