CAS NO: | 251565-85-2 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 251565-85-2 |
别名 | (S)-2-乙氧基-3-{4-[2-(4-甲磺酰基苯基)-乙氧基-苯基]-丙酸 |
化学名 | (S)-2-ethoxy-3-(4-(4-((methylsulfonyl)oxy)phenethoxy)phenyl)propanoic acid |
Canonical SMILES | OC([C@H](CC(C=C1)=CC=C1OCCC(C=C2)=CC=C2OS(=O)(C)=O)OCC)=O |
分子式 | C20H24O7S |
分子量 | 408.47 |
溶解度 | DMF: 50 mg/ml,DMSO: 50 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml,Ethanol: 10 mg/ml |
储存条件 | Desiccate at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα, with EC50s of 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively, and approximately 0.2 μM for both rat and human PPARγ. Tesaglitazar induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats[1]. References: |