您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Tetramethylpyrazine
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Tetramethylpyrazine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tetramethylpyrazine图片
CAS NO:1124-11-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
四甲基吡嗪(川芎嗪),一种从川芎中分离出来的烷基吡嗪。
Cas No.1124-11-4
别名川芎嗪; Chuanxiongzine; Tetramethylpyrazine
化学名2,3,5,6-tetramethylpyrazine
Canonical SMILESCC1=C(N=C(C(=N1)C)C)C
分子式C8H12N2
分子量136.2
溶解度DMF: 5mg/mL,DMSO: 5mg/mL,Ethanol: 25mg/mL,Ethanol:PBS (pH 7.2) (1:5): 0.16mg/mL
储存条件Stored at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tetramethylpyrazine (Ligustrazine), an alkylpyrazine isolated from Ligusticum wallichii (Chuan Xiong)[1], is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Tetramethylpyrazine (Ligustrazine) also has potential nootropic and anti-inflammatory activities in rats[2][3].

Tetramethylpyrazine has been extensively used in China for cardiovascular and cerebrovascular diseases for about 40 years. Because of its effectiveness in multisystem, especially in cardiovascular. Tetramethylpyrazine also has been used in various diseases, such as coronary heart disease, diabetes, cancers, and liver injury[1].

References:
[1]. Zhao Y, et al. Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective. Oxid Med Cell Longev. 2016;2016:2124638.
[2]. Wu W, et al. Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway. Behav Brain Res. 2013 Sep 15;253:212-6.
[3]. Kao TK, et al. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp Neurol. 2013 Sep;247:188-201.