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蛋白质/抗原/多肽 >> 重组蛋白
重组Ras蛋白特异鸟嘌呤核苷酸释放因子4
重组Ras蛋白特异鸟嘌呤核苷酸释放因子4图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant RASGRP4
Recombinant RAS guanyl releasing protein 4 protein
产品介绍
基因名:

RASGRP4


产品别名:

RASGRP4; RAS guanyl releasing protein 4; RAS guanyl releasing protein 4; RAS guanyl-releasing protein 4; guanyl nucleotide releasing protein 4; Ras蛋白特异鸟嘌呤核苷酸释放因子4;


背景信息:
The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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