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蛋白质/抗原/多肽 >> 重组蛋白
重组GALNT13蛋白
重组GALNT13蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant GALNT13
Recombinant polypeptide N-acetylgalactosaminyltransferase 13 protein
产品介绍
基因名:

GALNT13


产品别名:

GalNAc-T13; GALNT13; polypeptide N-acetylgalactosaminyltransferase 13; polypeptide N-acetylgalactosaminyltransferase 13; polypeptide N-acetylgalactosaminyltransferase 13; GalNAc transferase 13; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13); polypeptide GalNAc transferase 13; polypeptide N-acetylgalactosaminyltransferase 13 variant delta39bpEx9; polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx2-7; polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx6 delta39bpEx9; polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx6 deltaEx8 delta39bpEx9; polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx8; polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx9; pp-GaNTase 13; protein-UDP acetylgalactosaminyltransferase 13;


背景信息:
The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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