蛋白质/抗原/多肽 >> 重组蛋白
重组甘露糖苷酶2蛋白
产品介绍 基因名: MANEA 产品别名: ENDO; hEndo; MANEA; mannosidase endo-alpha; mannosidase endo-alpha; glycoprotein endo-alpha-1,2-mannosidase; alpha 1,2-endomannosidase; endo-alpha mannosidase; endomannosidase; mandaselin; 甘露糖苷酶2; 背景信息: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008] 标签:His-tag |
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