蛋白质/抗原/多肽 >> 重组蛋白
重组卷曲螺旋结构域蛋白138
产品介绍 基因名: Ccdc138 产品别名: 6230424H07Rik; BC042726; Ccdc138; coiled-coil domain containing 138; coiled-coil domain containing 138; coiled-coil domain-containing protein 138; 卷曲螺旋结构域蛋白138; 背景信息: CCDC138, also known as FLJ32745, is a 685 amino acid protein expressed as two isoforms produced by alternative splicing. The gene that encodes CCDC138 maps to human chromosome 2q12.3. The second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. 标签:His-tag |
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