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蛋白质/抗原/多肽 >> 重组蛋白
重组HJURP蛋白
重组HJURP蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant HJURP
Recombinant Holliday junction recognition protein
产品介绍
基因名:

HJURP


产品别名:

FAKTS; URLC9; hFLEG1; HJURP; Holliday junction recognition protein; Holliday junction recognition protein; Holliday junction recognition protein; 14-3-3-associated AKT substrate; fetal liver expressing gene 1; fetal liver-expressing gene 1 protein; up-regulated in lung cancer 9; HJURP蛋白;


背景信息:
HJURP is a 748 amino acid protein that is expressed in thymus, placenta, small intestine, liver, skeletal muscle, bone marrow and colon. When histone H3-like variant CENP-A nucleosomes are assembled, HJURP localizes in centromeres during late telophase and early G1 phase, and localizes to the nucleolus during S phase. Considered a centromeric protein, HJURP plays a central role in the incorporation and maintenance of CENP-A at centromeres. HJURP also acts as a specific chaperone for CENP-A and is required for the incorporation of newly synthesized CENP-A molecules into nucleosomes at replicated centromeres. HJURP is considered an indispensable factor for chromosomal stability in immortalized cancer cells and is a potential novel therapeutic target for the development of anticancer drugs.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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