蛋白质/抗原/多肽 >> 重组蛋白
重组黑色素瘤抗原样基因2蛋白
产品介绍 基因名: Magel2 产品别名: Mage-l2; NDNL1; nM15; ns7; Magel2; MAGE family member L2; MAGE family member L2; MAGE-like protein 2; melanoma antigen, family L, 2; melanoma antigen-like gene 2; necdin-like 1; protein nS7; 黑色素瘤抗原样基因2; 背景信息: Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression. 标签:His-tag |
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