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蛋白质/抗原/多肽 >> 重组蛋白
重组氧化固醇结合蛋白4
重组氧化固醇结合蛋白4图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组氧固醇结合蛋白2(OSBP2)
Recombinant OSBP2
产品介绍
基因名:

OSBP2


产品别名:

HLM; ORP-4; ORP4; OSBPL1; OSBPL4; OSBP2; oxysterol binding protein 2; oxysterol binding protein 2; oxysterol-binding protein 2; OSBP-related protein 4; oxysterol binding protein-like 1; oxysterol-binding protein-related protein 4; 氧化固醇结合蛋白4; 氧固醇结合蛋白2(OSBP2);


背景信息:
The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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