蛋白质/抗原/多肽 >> 重组蛋白
重组原钙粘附蛋白α4
产品介绍 基因名: Pcdha4 产品别名: Cnr1; Crnr1; R75250; Pcdha4; protocadherin alpha 4; protocadherin alpha 4; protocadherin alpha-4; PCDH-alpha-4; cadherin-related neuronal receptor 1; 原钙粘附蛋白α4; 原钙黏素α4(PCDHa4); 背景信息: Members of the cadherin-related neuronal receptor (CNR) family, including PCDHA4 (also known as CNR1) and PCDHA6 (also known as CNR2), comprise a novel subfamily within the cadherin superfamily of adhesion molecules. The cadherin-related neuronal receptor proteins form a complex with Fyn, a protein tyrosine kinase that is involved in building brain networks and determining patterns of behavior. Cadherin-related neuronal receptor 1 and 2 were discovered during a search for receptor molecules to the Fyn signaling pathway in the mammalian brain. Members of the cadherin superfamily are Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The PCDHA4 and PCDHA6 extracellular domains contain six cadherin repeats that mediate Ca++-dependent cell adhesion, while the cytoplasmic domains are not homologous with other cadherins. 标签:His-tag |
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