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有机溶质转运蛋白OSTβ抗体
有机溶质转运蛋白OSTβ抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Anti-SLC51B
Anti-solute carrier family 51 subunit beta Antibody
产品介绍
靶标:

SLC51B


产品别名:

OSTB; OSTBETA; PBAM2; SLC51B; solute carrier family 51 subunit beta; solute carrier family 51 subunit beta; organic solute transporter subunit beta; OST-beta; organic solute transporter beta subunit; solute carrier family 51 beta subunit; 有机溶质转运蛋白OSTβ;


背景信息:
The heteromeric transporter OST Alpha OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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