产品介绍 靶标: MARCHF9 产品别名: MARCH-IX; MARCH9; RNF179; MARCHF9; membrane associated ring-CH-type finger 9; membrane associated ring-CH-type finger 9; E3 ubiquitin-protein ligase MARCHF9; E3 ubiquitin-protein ligase MARCH9; RING finger protein 179; RING-type E3 ubiquitin transferase MARCH9; RING-type E3 ubiquitin transferase MARCHF9; membrane associated ring finger 9; membrane-associated RING finger protein 9; membrane-associated RING-CH protein IX; membrane-associated ring finger (C3HC4) 9; 膜相关环指蛋白9; 背景信息: MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).[supplied by OMIM, Apr 2010], 宿主:Rbt |
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