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SPIRE2蛋白抗体
产品介绍 靶标: SPIRE2 产品别名: Spir-2; SPIRE2; spire type actin nucleation factor 2; spire type actin nucleation factor 2; protein spire homolog 2; spire actin nucleation factor 2; spire family actin nucleation factor 2; spire homolog 2; SPIRE2蛋白; 背景信息: Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (By similarity. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage. 宿主:Rbt |
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