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前细胞胀亡受体诱导膜损伤蛋白抗体
产品介绍 靶标: Tmem123 产品别名: 2310075C12Rik; Tmem123; transmembrane protein 123; transmembrane protein 123; porimin; pro-oncosis receptor inducing membrane injury; 前细胞胀亡受体诱导膜损伤蛋白; 背景信息: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008], 宿主:Rbt |
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