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FAM173B蛋白抗体
产品介绍 靶标: Atpsckmt 产品别名: A930016P21Rik; AA987072; Fam173b; mFam173b; Atpsckmt; ATP synthase C subunit lysine N-methyltransferase; ATP synthase C subunit lysine N-methyltransferase; ATP synthase subunit C lysine N-methyltransferase; family with sequence similarity 173, member B; protein FAM173B; protein N-lysine methyltransferase FAM173B; FAM173B蛋白; 背景信息: Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C, ATP5MC1 and ATP5MC2. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. Promotes chronic pain. Involved in persistent inflammatory and neuropathic pain: methyltransferase activity in the mitochondria of sensory neurons promotes chronic pain via a pathway that depends on the production of reactive oxygen species (ROS and on the engagement of spinal cord microglia. 宿主:Rbt |
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