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ICEBERG蛋白抗体
产品介绍 靶标: CARD18 产品别名: ICEBERG; UNQ5804; pseudo-ICE; CARD18; caspase recruitment domain family member 18; caspase recruitment domain family member 18; caspase recruitment domain-containing protein 18; ICEBERG caspase-1 inhibitor; caspase-1 inhibitor Iceberg; ICEBERG蛋白; 背景信息: CARD18 contains a caspase recruitment domain (CARD) via which it binds to caspase-1 and thereby inhibits caspase-1-mediated activation of the pro-inflammatory cytokine interleukin (IL)-1β. Caspase recruitment domain family member 18 (CARD18, Iceberg) is known as a negative regulatory molecule that inhibits inflammatory events by terminating inflammasome activation due to direct interaction with pro-caspase-1. CARD18 may contribute to the fine tuning of keratinocyte innate immune processes. 宿主:Rbt |
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