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连接介导调节蛋白抗体
连接介导调节蛋白抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Anti-Jmy
Anti-junction-mediating and regulatory protein Antibody
产品介绍
靶标:

Jmy


产品别名:

Jmy; junction-mediating and regulatory protein; junction-mediating and regulatory protein; junction-mediating and -regulatory protein; p300 transcriptional cofactor JMY; 连接介导调节蛋白;


背景信息:
function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage.,induction:By E2F.,PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response.,similarity:Contains 1 WH2 domain.,subunit:Interacts with p300/EP300, the complex being recruited to activated p53/TP53. Interacts with TTC5.,

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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