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TRMT1蛋白抗体
产品介绍 靶标: TRMT1 产品别名: MRT68; TRM1; TRMT1; tRNA methyltransferase 1; tRNA methyltransferase 1; tRNA (guanine(26)-N(2))-dimethyltransferase; N(2),N(2)-dimethylguanosine tRNA methyltransferase; TRM1 tRNA methyltransferase 1 homolog; tRNA 2,2-dimethylguanosine-26 methyltransferase; tRNA methyltransferase 1 homolog; tRNA(guanine-26,N(2)-N(2)) methyltransferase; tRNA(m(2,2)G26)dimethyltransferase; TRMT1蛋白; 背景信息: This gene encodes a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in this gene have been implicated in autosomal recessive intellectual disorder (ARID). Alternative splicing results in multiple transcript variants encoding different isoforms. There is a pseudogene of this gene on the X chromosome. 宿主:Rbt |
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