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FBXW5蛋白抗体
产品介绍 靶标: Fbxw5 产品别名: AI159739; Fbw5; Fbxw5; F-box and WD-40 domain protein 5; F-box and WD-40 domain protein 5; F-box/WD repeat-containing protein 5; F-box and WD-40 domain-containing protein 5; F-box protein Fbw5; FBXW5蛋白; 背景信息: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008], 宿主:Rbt |
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