产品介绍 靶标： KAT6B 产品别名： GTPTS； MORF； MOZ2； MYST4； ZC2HC6B； qkf； querkopf； KAT6B； lysine acetyltransferase 6B； lysine acetyltransferase 6B； histone acetyltransferase KAT6B； K(lysine) acetyltransferase 6B； MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4； MOZ-related factor； MYST histone acetyltransferase (monocytic leukemia) 4； MYST-4； histone acetyltransferase MORF； histone acetyltransferase MOZ2； histone acetyltransferase MYST4； monocytic leukemia zinc finger protein-related factor； 组蛋白乙酰转移酶MORF； 背景信息： The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012], 宿主：Rbt |
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