产品介绍 靶标: ST8SIA1 产品别名: GD3S; SIAT8; SIAT8-A; SIAT8A; ST8SiaI; ST8SIA1; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1; alpha-2,8-sialyltransferase 8A; disialoganglioside (GD3) synthase; ganglioside GD3 synthase; ganglioside GT3 synthase; ganglioside-specific alpha-2,8-polysialyltransferase; sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A; sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase); sialyltransferase St8Sia I; sialytransferase St8Sia I; 背景信息: Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. 宿主:Rbt |
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