AUH抗体

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AUH抗体


交货期:	1周
产品别名:	Anti-AUH Anti-AU RNA binding methylglutaconyl-CoA hydratase Antibody

产品介绍

靶标：

AUH

产品别名：

AUH； AU RNA binding methylglutaconyl-CoA hydratase； AU RNA binding methylglutaconyl-CoA hydratase； methylglutaconyl-CoA hydratase, mitochondrial； 3-MG-CoA hydratase； 3-methylglutaconyl-CoA hydratase； AU RNA binding protein/enoyl-CoA hydratase； AU RNA-binding protein/enoyl-Coenzyme A hydratase； AU-binding protein/Enoyl-CoA hydratase； AU-specific RNA-binding enoyl-CoA hydratase； itaconyl-CoA hydratase；

背景信息：

This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。