| CAS NO: | 1705602-02-3 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 生物活性 | GNE-4997 is a potent and selectiveinterleukin-2-inducible T-cell kinase (ITK)inhibitor with aKiof 0.09 nM, and the correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity[1]. |
| IC50& Target | Ki: 0.09 nM (ITK)[1] |
| 体外研究 (In Vitro) | GNE-4997 inhibits PLC-γ phosphorylation in Jurkat cells by T-cell receptor stimulation with an IC50of 4 nM[1]. |
| 分子量 | 515.58 |
| Formula | C25H27F2N5O3S |
| CAS 号 | 1705602-02-3 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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