CAS NO: | 180977-44-0 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
CAS: | 180977-44-0 |
分子式: | C27H33N3O3S |
分子量: | 479.63 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 3 μM (Rap1A, in vivo), > 20 μM (Ha-Ras, in vivo)[3] |
描述: | GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ra |