| CAS NO: | 5399-87-1 |
| 包装 | 价格(元) |
| 1 g | 电议 |
| 5 g | 电议 |
| Cas No. | 5399-87-1 |
| 别名 | 6-氯嘌呤核苷 |
| Canonical SMILES | ClC1=C(N=CN2[C@]3([H])O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1 |
| 分子式 | C10H11ClN4O4 |
| 分子量 | 286.7 |
| 溶解度 | DMF: 2 mg/ml,DMSO: 5 mg/ml,Ethanol: insol,PBS (pH 7.2): insol |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 6-Chloropurine riboside is a nucleoside precursor.1It has been used in the synthesis of adenosine derivatives with antiproliferative activity in human gastric cancer cells expressing the adenosine A3receptor. 6-Chloropurine riboside has also been used in the synthesis of N6-benzyladenosine derivatives with antiproliferative activity in a variety of cancer cells or inhibitory activity againstT. gondiireplication in CRL-1634/Hs27 human skin fibroblasts.2,3 1.Zurita, F.V., Vega, N.B., and Cabrera, M.G.Semisynthesis, characterization and evaluation of new adenosine derivatives as antiproliferative agentsMolecules23(5)1111(2018) 2.Dolezal, K., Popa, I., HauserovÁ, E., et al.Preparation, biological activity and endogenous occurrence of N6-benzyladenosinesBioorg. Med. Chem.15(11)3737-3747(2007) 3.Kim, Y.A., Sharon, A., Chu, C.K., et al.Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agentsBiochem. Pharmacol.73(10)1558-1572(2007) |
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