B022 是一种有效的选择性的 NF-κB 诱导激酶 (NIK) 抑制剂，Ki 为 4.2 nM。B022 可保护肝脏免受毒素引起的炎症，氧化应激和伤害。
货号:ajcx16334
CAS:1202764-53-1
分子式:C19H16ClN5OS
分子量：397.88
溶解度:DMSO: 250 mg/mL (628.33 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

B022 is a potent and selective NF-κB-inducing kinase (NIK) inhibitor with a Ki of 4.2 nM. B022 protects liver from toxin-induced inflammation, oxidative stress, and injury[1].

[1]. Ren X, et al. A small-molecule inhibitor of NF-κB-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury. FASEB J. 2017 Feb;31(2):711-718.