AZD4625 (Compound 21) 是一种高度有效的、选择性的、共价和变构的突变 GTPaseKRasG12C抑制剂。AZD4625 具有高口服生物利用度。

AZD4625 (Compound 21) is a highly potent, selective, covalent and allosteric inhibitor of the mutant GTPase KRAS G12C. AZD4625 has high oral bioavailability [1].

C24H21ClF2N4O3

486.9

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years