(R)-SCH 42495 is the less active enantiomer of SCH 42495. SCH 42495 is an orally bioavailable neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally bioavailable ethylester prodrug of SCH 42354. References: [1]. Neustadt BR, et al. Mercaptoacyl amino acid inhibitors of atriopeptidase. 1. Structure-activity relationship studies of methionine and S-alkylcysteine derivatives. J Med Chem. 1994 Jul 22;37(15):2461-76. [2]. Watkins RW, et al. Atrial natriuretic factor potentiating and hemodynamic effects of SCH 42495, a new, neutral metalloendopeptidase inhibitor. Am J Hypertens. 1993 May;6(5 Pt 1):357-68.

纯度：≥98%

CAS：156792-25-5