LenalIDOmide-OH 是一种用于 E3 泛素连接酶 (CRBN) 的 cereblon 配体 LenalIDOmide 的类似物，用于 CRBN 蛋白的募集。它能够利用 linker 连接到蛋白质配体上形成 PROTAC。

Lenalidomide-OH is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BTK degrader SJF620.

Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs which are the inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

1416990-08-3

C13H12N2O4

260.25

DMSO:11 mg/mL (42.27 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years