生物化学/生理学作用【Biochem/physiol Actions】 : Lanreotide acetate is a somatostatin analog, a selective agonist for the SRIF-1 sst2 subtype of somatostatin receptor with a binding affinity of 0.8 nM for sst2 compared to 5.2 nM for sst5, 100 nM for sst3 and more than 1000 nM for the SRIF-2 subtypes, sst1 and sst4 receptors. It is used clinically in the management of acromegaly and symptoms caused by neuroendocrine tumors, and in recent studies can also inhibit tumor growth and has shown activity against non-endocrine tumors.
含量【assay】 : ≥98% (HPLC)
形态【form】 : powder
颜色【color】 : white to off-white
装运【shipped in】 : wet ice
存储温度【storage temp.】 : -20℃
安全信息:
符号【Symbol】 : GHS08
信号词【Signal word】 : Warning
危害声明【Hazard statements】 : H361
警示性声明【Precautionary statements】 : P281
危害码(欧洲)【Hazard Codes (Europe)】 : Xn
风险声明(欧洲)【Risk Statements (Europe)】 : 63
安全声明(欧洲)【Safety Statements (Europe)】 : 36/37
德国水质危险性分类【WGK Germany】 : 3