重组巴尔得-别德尔综合征相关蛋白5
产品名称 Recombinant BBS1 Recombinant Bardet-Biedl syndrome 1 protein 产品介绍
基因名: BBS1 产品别名: BBS2L2; BBS1; Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 1 protein; BBS2-like protein 2; 巴尔得-别德尔综合征相关蛋白5; 背景信息: The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. 标签:His-tag 用户评论 产品评分 目前评分共0人 产品质量
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